Onglyza (Saxagliptin)
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Available Options
2.5mg
30 tablets
5mg
30 tablets
Important Information
- • A valid prescription is required for all orders
- • Orders are shipped within 3–7 business days
- • Express shipping with cold chain packaging to keep your medication safe and effective
Description
Onglyza is a prescription oral medication that contains saxagliptin, a DPP-4 (dipeptidyl peptidase-4) inhibitor used to control blood sugar levels in adults with Type 2 diabetes. It is designed to work alongside diet and exercise, either as a monotherapy or in combination with other antidiabetic medications.
Saxagliptin increases incretin levels in the body, which help stimulate insulin release and reduce glucagon levels when blood sugar is elevated. This leads to better post-meal glucose control without a significant risk of hypoglycemia when used alone.
Onglyza is not for the treatment of Type 1 diabetes or diabetic ketoacidosis.
Fact Table
| Formula | C18H25N5O2 |
|---|---|
| License | EU EMA, US FDA |
| Chemical Name | Saxagliptin |
| Dosage (Strength) |
|
| Route | Oral (by mouth) |
| Bioavailability | ~50% |
Directions
- Take Onglyza once daily with or without food.
- Swallow the tablet whole with water at the same time each day.
- Always follow your doctor’s dosing instructions. Dose adjustments may be necessary for patients with kidney impairment.
Ingredients
Each tablet contains Saxagliptin hydrochloride as the active ingredient, along with inactive ingredients such as lactose monohydrate, magnesium stearate, and cellulose derivatives.
Cautions
- Onglyza should not be used in patients with Type 1 diabetes or diabetic ketoacidosis.
- Use with caution in individuals with heart failure or impaired kidney function. Monitor blood glucose regularly.
- Store at room temperature (68–77°F / 20–25°C), protected from heat and moisture.
- Keep in the original packaging.
Interactions
May increase the risk of hypoglycemia when used with insulin or sulfonylureas. Inform your healthcare provider about all medications, supplements, and herbal products before starting Onglyza.
Side Effects
- Common: upper respiratory infections, urinary tract infections, and headache.
- Rare but serious: pancreatitis, allergic reactions, and heart failure. Seek medical attention if severe symptoms occur.
Frequently Asked Questions
What is Onglyza used for?
Onglyza is used to control blood sugar levels in adults with Type 2 diabetes.
How does Onglyza work?
It blocks the DPP-4 enzyme, increasing incretin hormones that help manage insulin and glucagon levels.
Can Onglyza be taken with metformin?
Yes, Onglyza is commonly used in combination with metformin for improved glycemic control.
Does Onglyza cause weight gain?
No, Onglyza is considered weight-neutral and does not typically lead to weight gain.
What are the side effects of Onglyza?
Common side effects include headache and respiratory infections. Serious effects may include pancreatitis and heart failure.
Is Onglyza safe for kidney disease?
Yes, but dose adjustment is recommended for patients with moderate to severe renal impairment.
How should Onglyza be taken?
Once daily, with or without food, preferably at the same time each day.
Is Onglyza approved internationally?
Yes, it is approved by the FDA, EMA, and many health authorities worldwide.
Can Onglyza be taken long-term?
Yes, Onglyza is approved for long-term use when prescribed appropriately.
How should I store Onglyza?
Store at room temperature and keep tablets dry and protected from heat.
Important Note
The information above is provided for educational purposes only and should not replace professional medical advice. Please consult a qualified healthcare provider for personalized guidance on medication safety, suitability, and proper use.