Trulicity (Dulaglutide)
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Available Options
0.75mg
4 pens
1.5mg
4 pens
3mg
4 pens
4.5mg
4 pens
Important Information
- • A valid prescription is required for all orders
- • Orders are shipped within 3–7 business days
- • Express shipping with cold chain packaging to keep your medication safe and effective
Description
Trulicity is a once-weekly injectable medication that contains dulaglutide, a GLP-1 receptor agonist approved for the treatment of Type 2 diabetes. It is designed to help adults manage blood sugar levels and reduce the risk of major cardiovascular events such as heart attack or stroke in individuals with diabetes and existing heart disease.
Dulaglutide mimics the effects of the natural GLP-1 hormone, which stimulates insulin secretion, reduces glucagon production, and slows gastric emptying. These actions contribute to better post-meal glucose control and a reduction in HbA1c levels. Trulicity may also support modest weight loss and is typically prescribed when diet, exercise, or other medications do not provide sufficient glycemic control.
Trulicity is not insulin and is not indicated for the treatment of Type 1 diabetes or diabetic ketoacidosis.
Fact Table
| Formula | C4020H6204N1088O1264C8 |
|---|---|
| License | EU EMA, US FDA |
| Chemical Name | Dulaglutide |
| Dosage (Strength) |
|
| Route | Subcutaneous injection |
| Bioavailability | ~65% |
Directions
- Inject Trulicity once a week on the same day, at any time of the day, with or without food.
- Administer subcutaneously in the abdomen, thigh, or upper arm.
- Start at the lowest dose and titrate as needed under medical supervision. Rotate injection sites weekly to avoid irritation.
Ingredients
The active ingredient in Trulicity is Dulaglutide, formulated in a ready-to-use, once-weekly pre-filled pen for subcutaneous injection.
Cautions
- Trulicity should not be used by individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Avoid if allergic to dulaglutide or any of its excipients.
- Patients should be monitored for signs of pancreatitis, kidney issues, and diabetic retinopathy complications.
- Store pens in the refrigerator (36–46°F / 2–8°C).
- After first use or if carried for travel, they may be kept at room temperature (below 86°F / 30°C) for up to 14 days.
Interactions
Trulicity may delay gastric emptying and impact absorption of oral medications. Inform your healthcare provider about all medications, including vitamins and supplements, before starting Trulicity.
Side Effects
- Common: nausea, diarrhea, vomiting, abdominal pain, and decreased appetite.
- Rare but serious: pancreatitis, kidney problems, and possible thyroid tumors. Contact a healthcare provider if you experience severe or persistent symptoms.
Frequently Asked Questions
What is Trulicity used for?
Trulicity is used to improve blood sugar control in adults with Type 2 diabetes and reduce the risk of cardiovascular events in those with heart disease.
How does Trulicity work?
Trulicity activates GLP-1 receptors to boost insulin release, reduce glucagon secretion, and slow digestion, which helps lower blood sugar after meals.
Is Trulicity insulin?
No, Trulicity is not insulin. It’s a GLP-1 receptor agonist that helps your body use its own insulin more effectively.
Can Trulicity help with weight loss?
Yes, some patients experience weight loss while on Trulicity, although it is primarily prescribed for blood sugar control.
How long does it take for Trulicity to start working?
Trulicity begins to affect blood sugar within the first few doses, with noticeable improvements typically seen in 4–6 weeks.
What are the side effects of Trulicity?
Common side effects include gastrointestinal discomfort, such as nausea and vomiting. Serious risks include pancreatitis and thyroid tumors.
Can I take Trulicity with metformin?
Yes, Trulicity is often prescribed alongside metformin or other oral antidiabetic medications, under medical supervision.
How is Trulicity different from Ozempic or Mounjaro?
Trulicity contains dulaglutide, whereas Ozempic has semaglutide and Mounjaro uses tirzepatide. Each varies in receptor activity and effectiveness.
Do I need to refrigerate Trulicity?
Yes, before first use. Afterward, it can be stored at room temperature for up to 14 days.
Is Trulicity approved internationally?
Yes, Trulicity is approved by regulatory authorities including the FDA (U.S.) and EMA (EU) for use in Type 2 diabetes.
Important Note
The information above is provided for educational purposes only and should not replace professional medical advice. Please consult a qualified healthcare provider for personalized guidance on medication safety, suitability, and proper use.