Xarelto (Rivaroxaban)
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Available Options
2.5mg
56 tablets
10mg
30 tablets
15mg
28 tablets
20mg
28 tablets
Important Information
- • A valid prescription is required for all orders
- • Orders are shipped within 3–7 business days
- • Express shipping with cold chain packaging to keep your medication safe and effective
Description
Xarelto is a prescription oral anticoagulant that contains rivaroxaban, a direct Factor Xa inhibitor. It is widely used to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE), and reduce the risk of clot formation following knee or hip replacement surgery.
Xarelto works by directly inhibiting Factor Xa, a key enzyme in the coagulation cascade, thereby reducing the formation of blood clots. Unlike traditional blood thinners like warfarin, Xarelto does not require routine INR monitoring and has fewer food interactions.
Dosing frequency and tablet strength vary depending on the indication and the individual patient profile.
Fact Table
| Formula | C19H18ClN3O5S |
|---|---|
| License | EU EMA, US FDA |
| Chemical Name | Rivaroxaban |
| Dosage (Strength) |
|
| Route | Oral (by mouth) |
| Bioavailability | ~80–100% (dose-dependent) |
Directions
- Take Xarelto exactly as prescribed by your healthcare provider.
- It may be taken with or without food, although higher doses (15 mg and 20 mg) should be taken with food to ensure absorption.
- Do not skip or double doses.
Ingredients
Each tablet contains Rivaroxaban as the active ingredient, along with inactive ingredients such as microcrystalline cellulose, croscarmellose sodium, and lactose monohydrate.
Cautions
- Do not use Xarelto if you have active bleeding, severe liver disease, or if you are allergic to rivaroxaban. Use caution in patients with renal impairment or those undergoing surgery.
- Stopping Xarelto suddenly can increase the risk of thrombotic events.
- Store at room temperature (68–77°F / 20–25°C) away from moisture and heat.
- Keep in original packaging until use.
Interactions
Xarelto may interact with drugs that affect blood clotting (e.g., NSAIDs, antiplatelets) or drugs affecting CYP3A4 and P-gp pathways. Always inform your doctor about all medications, supplements, or herbal products.
Side Effects
- Common: easy bruising, nosebleeds, and minor bleeding.
- Rare but serious: internal bleeding, hemorrhagic stroke, and allergic reactions. Seek immediate medical care for signs of major bleeding.
Frequently Asked Questions
What is Xarelto used for?
Xarelto is used to prevent and treat blood clots, reduce stroke risk in atrial fibrillation, and manage clot risk after orthopedic surgery.
How does Xarelto work?
It blocks Factor Xa, preventing the conversion of prothrombin to thrombin and reducing clot formation.
Does Xarelto require regular blood monitoring?
No, routine INR testing is not needed unlike with warfarin.
Can I take Xarelto with food?
Yes. Doses of 15 mg or more should be taken with food to improve absorption.
What happens if I miss a dose?
Take it as soon as you remember on the same day. Do not double up the next day.
Is Xarelto safe after surgery?
Yes, it’s often prescribed post-surgery to reduce the risk of DVT and PE after joint replacements.
What are the risks of taking Xarelto?
Risks include serious bleeding, especially if combined with other anticoagulants or NSAIDs.
Can I stop taking Xarelto suddenly?
No. Discontinuing suddenly can increase the risk of blood clots or stroke. Always consult your doctor.
Is Xarelto approved internationally?
Yes, it is approved by the FDA, EMA, and other regulatory authorities worldwide.
How should I store Xarelto?
Store at room temperature and keep it in the original container away from moisture.
Important Note
The information above is provided for educational purposes only and should not replace professional medical advice. Please consult a qualified healthcare provider for personalized guidance on medication safety, suitability, and proper use.